Hello, everyone. These three-day weekends are the best. This
weekend was perfect for work and play. Half of the weekend the
weather was horrible, perfect for studying, and the other half was
gorgeous, perfect for some daytime bar action. I took full
advantage of both aspects of the weekend.
This week, I thought I'd share an essay I wrote on the obesity
situation in our country and possible complimentary treatments that
we as alternative medicine practitioners could offer our
prospective patients. This is just my take on the situation and
treatment I believe could help, so please take it with a grain of
salt, and if anyone has any questions or comments, please shoot
them my way.
Obesity: A multifactorial disease in need of a
multifactorial treatment.
The most serious threat to public health in the United States
today can easily be attributed to chronic illness and health
problems either wholly or partially caused by diet. The estimated
number of deaths linked to obesity in the United States is 280,184
per year. Sixty-five percent of adults 20 years of age or older are
considered either overweight or obese. The leading cause of
mortality in our country is cardiovascular disease (38.5% of all
deaths). Cancer is the second leading cause of death in America
(25% of all deaths), one-third of which are ascribable to
nutritional factors and obesity (1). How has our society succumbed
to this modifiable risk factor of obesity? More importantly, how
can we combat this issue?
The first step in attacking this epidemic is to realize that
there is no one "magic bullet" to cure the overweight person. It
has been proven time after time, that monotherapies are not
effective. Obesity is a multifactorial disease in need of
multifactorial treatment. There are a slew of inherent barriers to
weight loss and controlling appetite. The most important of these
road blocks to health being the instinctual drive to eat,
hypothalamic inflammation, and regulation of satiation
hormones.
Chiropractic care and its philosophy of treating the whole
person, provides a unique and effective avenue in the world of
weight management. As a physician, one of our roles will be to use
education as a key component of treatment. We must relate to our
patients that overeating is instinctual, because historically, food
was a scarce commodity. Our genome has not had the time to adapt to
the fact that food is readily available to us.

In the time of our ancestors, the hunter-gatherers, the meal
they were eating could have very well been their last. The body
therefore creates a set point of weight over time to preserve
itself. In the obese, this set point is set at an increased weight
(1-2). This method was advantageous to the lean person in an
environment where food is scarce and physical activity was needed
to produce a meal. In society today, where over-processed fast food
is so readily available and little if any physical activity is
required to gather, weight gain isn't that surprising. Educating
our patients to the fact that weight management is an active
process should be the first step in treatment.
Education provides a solid base from which to build a healthier
society. The next tier of treatment is aimed to combat the
postprandial inflammation that occurs in the hypothalamus. It has
been studied and published, that systemic, and hypothalamic
inflammation can affect key neuronal systems that govern energy
homeostasis, and defend the level of body weight (3). Seventy-two
percent of the total daily energy consumed by an average American
consists of dairy, cereals, refined sugars, refined vegetable oils
and alcohol (1). These dietary choices translate to release of the
amino acid, arachidonic acid during their digestion, which leads to
the advent of inflammation in the body. This global inflammation
leads to disruption of satiety mechanism, via insulin/leptin
resistance, so people feel hungry even if they overeat (3). Diet
modification is key in this component of treatment.
A Paleo-Mediterranean diet has been shown to satiate as well as
keep levels of inflammatory mediators at a minimum (5). This
proposed diet, takes the best of the "Paleo" and Mediterranean"
style diets, with emphasis on fresh whole fruits, vegetables (raw
or minimally cooked), omega-3-rich lean meats, seeds, olive oil,
red wine in moderation, and the avoidance of starchy foods. This
diet has been consistently associated with improvements in insulin
sensitivity and reductions of cardiovascular disease, diabetes, and
cancer (5). Foods included in this diet provide the patient with
adequate nutrients, anti-inflammatories, anti-oxidants, as well as
favorably modifies gut microbiota. By providing our bodies with the
whole foods it needs, in a form that it is genetically equipped to
process, health and obesity is ours to control.
As much as our diets promote obesity, our mood contributes just
as much. Stress and lack of sleep promote increased ghrelin release
from the stomach (4). Ghrelin is a hormone that has the ability to
up-regulate appetite and down-regulate satiety by decreasing
insulin release. In order to fight back against ghrelin, it is
imperative to have patients get six to nine hours of sleep a night
(4), and manage their stress preferably with exercise, or
meditation.
A country composed of healthier people is a very attainable
goal, but it requires work by all parties. Managing this public
health issue will be effective if a multifactorial approach is used
to attack it. By educating our patients that they will have an
innate drive to overeat that they will have to overcome, providing
them with adequate anti-inflammatory diet options, and helping them
overcome stress and sleep deprivation, the obesity epidemic in our
country could be controlled. Weight gain and a healthy lifestyle
are modifiable risk factors that can be used to save over 250,000
lives per year (1).
References:
- Loren Cordain, S Boyd Eaton, Anthony Sebastian, Neil Mann,
Staffan Lindeberg, Bruce A Watkins, James H O'Keefe, and Janette
Brand-Miller."Origins and evolution of the Western diet: health
implications for the 21st century". American Journal of Clinical
Nutrition2005; 81:341-54.
- Sumithram P et al. "Long-term persistence of hormonal
adaptations to weight loss". New Eng J Med. 2011.
- Wisse BE, Schwartz MW. "Does hypothalamic inflammation cause
obesity?" Cell Metab. 2009; 10:241-42.
- Lisa Morselli, Rachel Leproult, Marcella Balbo, Karine Spiegel.
" Role of sleep duration in the regulation of glucose metabolism
and appetite". Endocr Dev. 2010; 17:11-21.
- Vasquez, A. "Integrative Rheumatology. Concepts, Perspectives,
Algorithms, and Protocols. 2nd edition. 2007;
90-92.
I hope everyone has a great week, and enjoyed the essay. If
nothing else, maybe it will give you something to consider with
future patients.
Catch ya on the flip side,
Dex